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1.3.1.1
metabolism
efficacy of the chemotherapeutic drug 5'-fluorouracil is reduced by catabolism to 2'-fluoro-beta-alanine, a three-step reaction in which dihydropyrimidine dehydrogenase catalyzes the rate limiting step
712566
1.3.1.1
physiological function
the enzyme is essential for the adaption of Entamoeba histolytica to long-term glucose starvation
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740276
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