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EC Number General Information Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 1.14.19.9metabolism tryptophan 7-halogenase catalyzes chlorination of free tryptophan to 7-chlorotryptophan, which is the first step in the antibiotic pyrrolnitrin biosynthesis 746470
Display the word mapDisplay the reaction diagram Show all sequences 1.14.19.9metabolism tryptophan 7-halogenase catalyzes chlorination of free tryptophan to 7-chlorotryptophan, which is the first step in the antibiotic pyrrolnitrin biosynthesis. Purified KtzQ and KtzR are tandem acting halogenases that catalyze the regiospecific dichlorination of L-tryptophan to produce 6,7-dichloro-L-tryptophan, KtzQ is specific for L-Trp or 6-chloro-L-Trp halogenation at C-7, while KtzR is specific for halogenation of C-6 of 7-chloro-L-Trp 745152
Display the word mapDisplay the reaction diagram Show all sequences 1.14.19.9physiological function enzyme KtzQ (along with the flavin reductase KtzS) acts to chlorinate at the 7-position of L-tryptophan 745152
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