EC Number |
General Information |
Reference |
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1.14.19.45 | evolution |
bifunctional DELTA12/DELTA15-desaturases are widely found in fungi species belonging to Ascomycota and Basidiomycota. Enzyme RKD12 shares higher homology to the Cop-odeA, it only exhibits DELTA12 and DELTA15 desaturation activity on C18 substrates without preference |
-, 744576 |
1.14.19.45 | evolution |
three different copies of the genes FAD2 and FAD3 are identified, which contain three histidine rich motifs (HXCGHX, HRXHH andHVXHH) and six highly conserved transmembrane domains. Comparing their sequences, the CsFAD2copies accommodate four conservative changes (E36D, R48H, V97A, and A177P) and two semi-conservative ones (V63I and L249M), whereas only one semi-conservative change (A327S) is detected in CsFAD3 but with two extra amino acids (H147 and G148) |
745061 |
1.14.19.45 | metabolism |
Solanum tuberosum L., cv. Desnitsa plants of wild type are transformed with desA gene of DELTA12-acyl-lipid desaturase from Synechocystis sp. PCC 6803. The transformed plants differ from the wild-type by elevated polyunsaturated fatty acids content in membrane lipids and greater resistance to oxidative stress under hypothermia |
746428 |
1.14.19.45 | metabolism |
the enzyme is involved in the biosynthesis of linoleic acid |
-, 745028 |
1.14.19.45 | physiological function |
DELTA12-fatty acid desaturase CpFAD2 from Candida parapsilosis is a multifunctional desaturase producing a range of polyunsaturated and hydroxylated fatty acids |
-, 746264 |
1.14.19.45 | physiological function |
for better adaptation to low temperatures, YM25235 may have evolved some adaptative mechanisms that might include the alteration of unsaturation levels of fatty acids in membrane lipids involving th enzyme |
-, 744576 |
1.14.19.45 | physiological function |
increased RKD12 mRNA expression level and PUFAs content at low temperature might be helpful for the cold adaptation of Rhodosporidium kratochvilovae YM25235 |
-, 744576 |
1.14.19.45 | physiological function |
the enzyme is involved in growth of Yarrowia lipolytica at low temperature |
744244 |