EC Number   |
General Information |
Reference |
|---|
   1.14.19.31 | evolution |
the enzyme belongs to the front-end desaturases |
-, 733779 |
| 1.14.19.31 | evolution |
the enzyme belongs to the front-end desaturases, phylogenetic analysis and tree, overview. Introns appear to have evolved independently among Tpdes genes |
658684 |
| 1.14.19.31 | evolution |
the enzyme belongs to the front-end desaturases, phylogenetic analysis, overview. The HX3HH motif can be used to a priori characterize the enzyme as front-end DELTA4 desaturase |
-, 673544 |
| 1.14.19.31 | malfunction |
enzyme knockdown lines show decreases in the 16:4 and 18:3-9,12,15 acyl groups in lipids, fatty acid profile, overview |
733753 |
| 1.14.19.31 | metabolism |
the enzyme is involved in docosahexaenoic acid synthesis pathway in the teleost Solea senegalensis |
744399 |
| 1.14.19.31 | metabolism |
the enzyme is involved in production of the health beneficial polyunsaturated fatty acid docosahexaenoic acid |
658684 |
| 1.14.19.31 | metabolism |
the enzyme is involved in the biosynthesis of docosahexanoic acid |
-, 732026 |
| 1.14.19.31 | metabolism |
the enzyme is involved in the pathway for very-long-chain polyunsaturated fatty acid biosynthesis existing in the protozoan. The enzymes involved in polyunsaturated fatty acid biosynthesis (i.e. DELTA6, DELTA8, DELTA5 and DELTA4 desaturases) are named front-end desaturases, because they introduce a double bond between a pre-existent olefinic bond and the carboxyl end of the fatty acid molecule. A complete pathway for very-long-chain polyunsaturated fatty acid biosynthesis is functional in Leishmania major using DELTA6, DELTA5 and DELTA4 desaturases |
-, 673544 |
| 1.14.19.31 | metabolism |
the enzymes involved in polyunsaturated fatty acid biosynthesis (i.e. DELTA6, DELTA8, DELTA5 and DELTA4 desaturases) are named front-end desaturases, because they introduce a double bond between a pre-existent olefinic bond and the carboxyl end of the fatty acid molecule. In trypanosomes, only DELTA4-desaturases are present from a complete pathway for very-long-chain polyunsaturated fatty acid biosynthesis |
-, 673544 |
| 1.14.19.31 | metabolism |
the enzymes involved in polyunsaturated fatty acid biosynthesis (i.e. DELTA6, DELTA8, DELTA5 and DELTA4 desaturases) are named front-end desaturases, because they introduce a double bond between a pre-existent olefinic bond and the carboxyl end of the fatty acid molecule. In trypanosomes, only DELTA4-desaturases are present from a complete pathway for very-long-chain polyunsaturated fatty acid biosynthesis, the enzyme is also able to use n-3 and n-6 fatty acid isomers |
-, 673544 |
