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EC Number General Information Commentary Reference
Show all pathways known for 1.14.15.18Display the word mapDisplay the reaction diagram Show all sequences 1.14.15.18malfunction Hypercalcaemia in subcutaneous fat necrosis appears to be due to abundant levels of 25-hydroxyvitamin D3-1alpha-hydroxylase in immune infiltrates associated with tissue lesions 697022
Show all pathways known for 1.14.15.18Display the word mapDisplay the reaction diagram Show all sequences 1.14.15.18more 25OHD action involves localized extrarenal conversion to 1,25-dihydroxyvitamin D via tissue-specific expression of the enzyme 25-hydroxyvitamin D-1alpha-hydroxylase. Expression of 1alpha-hydroxylase is intimately associated with toll-like receptor, TLR, recognition of pathogens in macrophages 712885
Show all pathways known for 1.14.15.18Display the word mapDisplay the reaction diagram Show all sequences 1.14.15.18physiological function mechanisms for involvement of 1alpha-hydroxylase in antimicrobial responses within different barrier tissues, overview 712885
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