EC Number |
General Information |
Reference |
---|
1.14.11.79 | evolution |
MINA53 belongs to a group of JmjC 2OG-oxygenases that does not contain other obvious functional domains |
764446 |
1.14.11.79 | evolution |
NO66 belongs to a group of JmjC 2OG-oxygenases that does not contain other obvious functional domains |
764446 |
1.14.11.79 | physiological function |
enzyme catalyzes the hydroxylation of L-histidine residues in the 60S ribosomal protein Rpl8. Also catalyzes histone L-lysine demethylation activities, demethylates histone H3 residues H3K4me and H3K36me, i.e. activities of ECs 1.14.11.67 and 1.14.11.27, respectively |
765443 |
1.14.11.79 | physiological function |
enzyme catalyzes the hydroxylation of L-histidine residues in the 60S ribosomal protein Rpl8. Also catalyzes histone L-lysine demethylation activities, demethylates histone H3 residues H3K9me3, i.e. activity of EC 1.14.11.66 |
765443 |
1.14.11.79 | physiological function |
NO66 hydroxylation reaction serves to properly orientate the 28S rRNA in the vicinity of the peptidyl transferase center |
764446 |