Any feedback?
Please rate this page
(search_result.php)
(0/150)

BRENDA support

Refine search

Search General Information

show results
Don't show organism specific information (fast!)
Search organism in taxonomic tree (slow, choose "exact" as search mode, e.g. "mammalia" for rat,human,monkey,...)
(Not possible to combine with the first option)
Refine your search

Search term:

Results 1 - 7 of 7
EC Number General Information Commentary Reference
Show all pathways known for 1.13.12.3Display the word mapDisplay the reaction diagram Show all sequences 1.13.12.3malfunction transient silencing of the tryptophan 2-monooxygenase-encoding gene iaaM in infected wheat plants indicates that it is required for full pathogenicity -, 745813
Show all pathways known for 1.13.12.3Display the word mapDisplay the reaction diagram Show all sequences 1.13.12.3metabolism identification of indole 3-acetamide and tryptophan monooxygenase activity suggests indole 3-acetamide routed indole 3-acetic acid (IAA) biosynthesis in Rubrivivax benzoatilyticus JA2 726752
Show all pathways known for 1.13.12.3Display the word mapDisplay the reaction diagram Show all sequences 1.13.12.3metabolism the enzyme is involved in the biosynthesis of auxin -, 746273
Show all pathways known for 1.13.12.3Display the word mapDisplay the reaction diagram Show all sequences 1.13.12.3metabolism tryptophan aminotransferase (TAT) and tryptophan 2-monooxygenase (TMO) participate in first step of tryptophan catabolism leading to the formation of indole acetic acid. Indole biosynthesis in strain JA2 occurs via the de novo shikimate pathway. Induction of tryptophan aminotransferase and tryptophan 2-monooxygenase activities corroborates well with indole 3-acetic acid levels, suggesting that tryptophan catabolism occurs simultaneously in aniline exposed cells. Aniline (stress) stimulates tryptophan/indoles synthesis via the shikimate pathway by possibly modulating the metabolic pathway -, 746257
Show all pathways known for 1.13.12.3Display the word mapDisplay the reaction diagram Show all sequences 1.13.12.3physiological function Crown gall development requires the expression of agrobacterial genes in the plant host, e.g. Arabidopsis thaliana. These genes are transferred by the T-DNA of the plant pathogen Agrobacterium tumefaciens and include the oncogenes IaaH, IaaM and Ipt, which, according to the tumor-inducing principle, are essential for crown gall development. Virulent Agrobacterium tumefaciens strains integrate their T-DNA into the plant genome where the encoded agrobacterial oncogenes are expressed and cause crown gall disease. Essential for crown gall development are IaaH (indole-3-acetamide hydrolase), IaaM (tryptophan monooxygenase) and Ipt (isopentenyl transferase), which encode enzymes for the biosynthesis of auxin (IaaH, IaaM) and cytokinin (Ipt). The oncogenes are involved in auxin and cytokinin production. The intergenic regions (IGRs) between the coding sequences (CDS) of the three oncogenes function as promoters in plant cells, but gene IaaM is constitutively expressed and no transcription factor further activates its promoter. With increasing auxin levels triggered by ubiquitous expression of IaaH and IaaM, ARF5 is activated and interacts with WRKY40 to potentiate Ipt expression and balance cytokinin and auxin levels for further cell proliferation. Transcriptional regulation of the Agrobacterium tumefaciens genes IaaH, IaaM and Ipt in the host plant, detailed overview -, 746273
Show all pathways known for 1.13.12.3Display the word mapDisplay the reaction diagram Show all sequences 1.13.12.3physiological function tryptophan 2-monooxygenase (TMO) participate in first step of tryptophan catabolism leading to the formation of indole acetic acid. Metabolic profiling reveals tryptophan accumulation only in aniline exposed cells along with indole 3-acetic acid and indole 3-aldehyde, the two major catabolites of tryptophan. Deuterium labelled aniline feeding studies reveal that while fumarate is the precursor of indole biosynthesis, aniline is not a precursor of indoles in strain JA2, but is an indole biosynthesis stimulator -, 746257
Show all pathways known for 1.13.12.3Display the word mapDisplay the reaction diagram Show all sequences 1.13.12.3physiological function tryptophan 2-monooxygenase from Puccinia graminis f. sp. tritici produces the auxin precursor indole-3-acetamide (IAM) and is involved in auxin biosynthesis and rust pathogenicity. Auxin acts as a regulator of plant growth and development but its production can also affect plant–microbe interactions. Expression of Pgt-IaaM in Arabidopsis thaliana haustoria causes a typical auxin expression phenotype and promotes susceptibility to the bacterial pathogen Pseudomonas syringae pv. tomato DC3000 -, 745813
Results 1 - 7 of 7