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Results 1 - 3 of 3
EC Number General Information Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 1.1.98.3physiological function construction of a conditional gene knockout strain targeting the gene encoding subunit dprE1 of decaprenylphosphoribose 2' epimerase. The gene is essential for viability, results suggests that decaprenylphosphoryl arabinose synthesis is essential in mycobacteria, indicate a lack of redundancy in decaprenylphosphoryl arabinose synthesis and suggest that no alternative arabinose donors for cell wall biosynthesis exist 720817
Display the word mapDisplay the reaction diagram Show all sequences 1.1.98.3physiological function decaprenylphosphoryl-beta-D-ribofuranose 2'-epimerase is constituted of DprE1 and DprE2 that together catalyze the epimerization of decaprenylphosphoryl-beta-D-ribofuranose to decaprenylphosphoryl-beta-D-arabinofuranose 719666
Display the word mapDisplay the reaction diagram Show all sequences 1.1.98.3physiological function decaprenylphosphoryl-D-arabinofuranose is synthesized by the following sequence of events: 5-phosphoribose 1-diphosphate is transferred to a decaprenyl-phosphate molecule to form decaprenylphosphoryl-beta-D-5-phosphoribose. Decaprenylphosphoryl-beta-D-5-phosphoribose is dephosphorylated to form decaprenylphosphoryl-beta-D-ribose. The hydroxyl group at the 2 position of the ribose is oxidized and is likely to form decaprenylphosphoryl-2-keto-beta-D-erythro-pentofuranose. Decaprenylphosphoryl-2-keto-beta-D-erythro-pentofuranose is reduced to form decaprenylphosphoryl-beta-D-arabinofuranose. Thus, the epimerization of the ribosyl to an arabinosyl residue occurs at the lipid-linked level -, 719703
Results 1 - 3 of 3