EC Number |
General Information |
Reference |
---|
1.1.3.47 | evolution |
the enzyme is a member of the glucosemethanol-choline oxidase (GMC) oxidoreductase superfamily and the AAO family. Phylogenetic analysis of the AAOs in Pleurotus ostreatous revealed that they cluster into two groups |
-, 742155 |
1.1.3.47 | malfunction |
mutants with a disrupted hmfH gene accumulate 5-hydroxymethylfuroic acid when cultured in the presence of 5-(hydroxymethyl)furfural |
730806 |
1.1.3.47 | metabolism |
the enzyme is important in the 5-hydroxymethylfurfural degradation pathway, verview |
742493 |
1.1.3.47 | metabolism |
the enzyme is involved in degradation of 5-(hydroxymethyl)furfural |
730806 |
1.1.3.47 | metabolism |
the enzyme is involved in the degradation and detoxification of 5-(hydroxymethyl)furfural |
729040 |
1.1.3.47 | physiological function |
Pleurotus ostreatus is capable to metabolize and detoxify 5-hydroxymethylfurfural at 30 mM within 48 h, converting it into 2,5-bis-hydroxymethylfuran and 2,5-furandicarboxylic acid. Two enzymes groups, which belong to the ligninolytic system, aryl-alcohol oxidases and a dehydrogenase, are involved in this process. 5-Hydroxymethylfurfural induces the transcription and production of these enzymes, accompanied by an increase in activity levels |
-, 742155 |
1.1.3.47 | physiological function |
the enzyme is involved in lignin degradation. Within this multienzymatic process, which enables the recycling of carbon fixed by photosynthesis in land ecosystems, AAO reduces O2, providing the H2O2 required by ligninolytic peroxidases to oxidize the recalcitrant lignin polymer |
742493 |
1.1.3.47 | physiological function |
the enzyme is involved in the degradation of 5-hydroxymethylfurfural. Two enzymes groups, which belong to the ligninolytic system, aryl-alcohol oxidase and a dehydrogenase, are involved in this process |
-, 742155 |