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1.1.1.305
evolution
the ancestral enzyme of UDP-xylose synthase and UDP-apiose/UDP-xylose synthase is diverged to two distinct enzymatic activities in early bacteria. This separation gave rise to the current UDP-xylose synthase in animal, fungus, and plant as well as to the plant Uaxs and bacterial ArnA and U4kpxs homologues
725414
1.1.1.305
evolution
the enzyme is a member of the short-chain dehydrogenase/reductase family of nucleotide-sugar modifying enzymes
724362
1.1.1.305
more
induced-fit conformational change associated with cofactor binding, overview
724362
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