EC Number   |
General Information |
Reference |
|---|
   1.1.1.219 | evolution |
DFR gene, which encodes dihyroflavonol 4-reductase, is the candidate gene for the anthocyaninless (ANL) locus in RCBr. DFR shows complete linkage with ANL in genetic crosses with a total of 948 informative chromosomes |
-, 741258 |
| 1.1.1.219 | evolution |
the enzyme belongs to the plant DFR superfamily, phylogenetic analysis |
725929 |
| 1.1.1.219 | evolution |
three DFR cDNA clones GbDFRs occur in the gymnosperm Ginkgo biloba. The deduced GbDFR proteins show high identities to other plant DFRs, which form three distinct DFR families. The three GbDFRs each belong to a different DFR family. Phylogenetic tree analysis reveals that the GbDFRs share the same ancestor as other DFRs |
741277 |
| 1.1.1.219 | malfunction |
downregulation of IbDFR expression in transgenic sweet potato (DFRi) using an RNAi approach dramatically reduces anthocyanin accumulation in young leaves, stems and storage roots. The increase of flavonols quercetin-3-O-hexose-hexoside and quercetin-3-O-glucoside in the leaves and roots of DFRi plants is significant. The metabolic pathway channels greater flavonol influx in the DFRi plants when their anthocyanin and proanthocyanidin accumulation are decreased. These plants also display reduced antioxidant capacity compared to the wild-type. After 24 h of cold treatment and 2 h recovery, the wild-type plants are almost fully restored to the initial phenotype compared to the slower recovery of DFRi plants, in which the levels of electrolyte leakage and hydrogen peroxide accumulation are dramatically increased |
741282 |
| 1.1.1.219 | malfunction |
overexpressing the Triticum aestivum dihydroflavonol 4-reductase gene TaDFR increases anthocyanin accumulation in an Arabidopsis thaliana dfr mutant |
740511 |
| 1.1.1.219 | malfunction |
overexpression of McDFR, or silencing of McFLS, increases anthocyanin production, resulting in red-leaf and red fruit peel phenotypes, while overexpression of McFLS, or silencing of McDFR, increase anthocyanin production, resulting in red-leaf and red fruit peel phenotypes |
741410 |
| 1.1.1.219 | malfunction |
strain DWRCBr57 with the recessive nonpurple phenotype has a transposon-related insertion in the DFR which is predicted to disrupt gene function. Non-purple strains bear an insertion mutation in exon 4 of the DFR gene. Some purple plants have an insertion mutation in the last intron |
-, 741258 |
| 1.1.1.219 | metabolism |
dihydroflavonol 4-reductase, McDFR, and flavonol synthase, McFLS, are important determinants of the red color of crabapple leaves, via the regulation of the metabolic fate of substrates that these enzymes have in common. Flavonoid biosynthetic pathway in plant, overview |
741410 |
| 1.1.1.219 | metabolism |
dihydroflavonol-4-reductase (DFR) is a key enzyme in the catalysis of the stereospecific reduction of dihydroflavonols to leucoanthocyanidins in anthocyanin biosynthesis |
741282 |
| 1.1.1.219 | metabolism |
key regulatory enzyme of the flavonoid pathway |
704148 |
