EC Number   |
General Information |
Reference |
|---|
    1.1.1.170 | malfunction |
a I/LnJ-specific nonsynonymous polymorphism in X-linked Nsdhl, which codes for sterol-4-alpha-carboxylate 3-dehydrogenase in the cholesterol synthesis pathway, causes reduced HDL cholesterol levels in plasma |
740499 |
| 1.1.1.170 | malfunction |
mutations in NSDHL gene are associated with human CHILD syndrome, congenital hemidysplasia with ichthyosiform nevus and limb defects |
722377 |
| 1.1.1.170 | metabolism |
the enzyme sterol-4-alpha-carboxylate 3-dehydrogenase is important in the cholesterol synthesis pathway |
740499 |
| 1.1.1.170 | metabolism |
the sterol-4-alpha-carboxylate-3-dehydrogenase is an essential enzyme in the ergosterol/cholesterol biosynthesis pathway |
-, 741051 |
| 1.1.1.170 | more |
ERG26p structure homology modeling based on the crystal structure of Pseudomonas aeruginosa UDP-N-acetylglucosamine 4-epimerase complexed with UDP-N-acetylgalactosamine, PDB ID 1SB8 |
-, 741051 |
| 1.1.1.170 | more |
HDL and non-HDL lipid contents in different mouse genotypes and correlation to gene Nsdhl, overview |
740499 |
| 1.1.1.170 | physiological function |
the sterol-4-alpha-carboxylate-3-dehydrogenase is an essential enzyme in the ergosterol/cholesterol biosynthesis pathway |
-, 741051 |
