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Results 1 - 10 of 35 > >>
EC Number
General Information
Commentary
Reference
malfunction
calpain 2 depletion impairs mitosis and induces apoptosis, low Capn2 levels induce chromosome alignment defects, the loss of histone H3 threonine 3 phosphorylation at centromeres, and premature sister chromatid separation
malfunction
calpain 2 knockdown in breast cancer cells correlates with reduced in vitro proliferation, migration, and in vivo tumorigenicity as well as reduced Akt activation, increased nuclear FoxO localization, and increased p27Kip1 expression
malfunction
calpain inhibition blocks the increased colonic epithelial cell invasion caused by NM IIA knockdown
malfunction
calpain inhibition favors differentiation of neuronal stem cells. Calpain 2 silencing elicits decreased levels of glial fibrillary acidic protein
malfunction
in vivo knockdown of calpain2 disrupts metastasis among apoptosis-resistant tumors
malfunction
inhibition of calpain activity limits cell migration and in vitro wound healing of IEC-6 cells
malfunction
inhibition of m-calpain induces expression of the adult alpha- and beta-globin genes
malfunction
knockdown of calpain 2 expression or chemical inhibition of calpain activity reduces glioblastoma cell invasion by 90%. Decreased expression of calpain 2 does not influence morphology or migration
malfunction
knockdown of calpain 2 inhibits T cell migration at both the level of single cell tracking and general cell speed
malfunction
knockdown of calpain 2 results in a 2.9fold decrease in the invasion of human glioblastoma cells in zebrafish brain. Calpain 2 knockdown cells demonstrate a 2.3fold lower area of dispersal compared with control cells
Results 1 - 10 of 35 > >>