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Results 1 - 10 of 14 > >>
EC Number General Information Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.43physiological function expression of CTSV rescues the reduced frequency of CD4+ T cells in cysteine protease cathepsin L-deficient mice with H-2b haplotype 707591
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.43physiological function CTSV is involved in the breakdown of corneodesmosomal proteins 709405
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.43metabolism cathepsin V participates in the production of enkephalin and neuropeptide Y neurotransmitters in secretory vesicles 732049
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.43malfunction RNAi-mediated depletion of the enzyme effectively abrogates ectopic E2F1-induced apoptosis, coupled with reduced lysosomal membrane permeabilization and mitochondrial membrane depolarization. Enzyme knockdown also inhibits apoptosis mediated by the endogenous E2F1 activated by DNA damage. Enzyme depletion in cancer cells results in inhibition of histone deacetylase inhibitor-induced apoptosis 732591
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.43physiological function cathepsin like 2 is required for E2F1-induced apoptosis by engaging lysosomal membrane permeabilization. Its level also modulates the cellular sensitivity to histone deacetylase inhibitor 732591
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.43malfunction lack of cathepsins prevent the development of lung granulomas in a mouse model of Besnier-Boeck-Schaumann (BBS) disease, sarcoidosis. Cathepsin V (Cath V) in bronchoalveolar lavage fluid (BALF) in humans 752418
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.43metabolism cathepsin V and endostatin may represent an index of pulmonary sarcoidosis activity 752418
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.43malfunction melanosome degradation is suppressed in CTSV knockdown cells. Inhibition of CTSV expression increases melanosome accumulation in HaCaT keratinocytes. The rate of melanosome degradation is reduced in CTSV knockdown keratinocytes 752678
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.43physiological function enzyme cathepsin V (CTSV) is involved in melanosome degradation in the keratinocytes derived from lightcolored skin. It is one of the factors regulating pigmentation 752678
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.43malfunction increased cathepsin V promoted the degradation of DUSP6 and DUSP7, phosphorylation and subsequent nuclear translocation of ERK1/2, phosphorylation of STAT1 and expression of interleukin (IL)-6, IL-8 and TNF-alpha 753117
Results 1 - 10 of 14 > >>