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Results 1 - 5 of 5
EC Number General Information Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.14metabolism active actinidin retains its primary structure and proteolytic activity after 2 h of simulated gastric digestion, followed by 2 h of intestinal digestion 734567
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.14more the enzyme increases intestinal permeability in both in vivo (mice) and in vitro (Caco-2 cell culture) models. The food allergen with intrinsic proteolytic activity can compromise the gut epithelial barrier, contributing to the sensitization process in food allergy pathogenesis 752807
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.14physiological function actinidin disrupts the epithelial barrier function of human intestinal T84 cells by degrading the tight junction protein occludin. Exposure of T84 cells to biologically active actinidin significantly decreases the transepithelial resistance across the intestinal epithelial monolayers 733900
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.14physiological function actinidin is both immunogenic and allergenic at relatively low doses. Vigorous IgG and IgG1 antibody and high titre IgE antibody responses are recorded in response to actinidin 734050
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.14physiological function actinidin is important in monoallergy to kiwifruit 708861
Results 1 - 5 of 5