EC Number   |
General Information |
Reference |
|---|
    5.1.3.19 | physiological function |
DS-epi2 and DS-epi1 are both involved in the biosynthesis of the iduronic acid blocks in fibroblasts and that DS-epi2 can also synthesize the hybrid structures |
704644 |
| 5.1.3.19 | physiological function |
isoform DS-epi2 plays key roles in the epimerization of chondroitin sulfate and dermatan sulfate during its biosynthesis. The L-iduronate-containing structures in the developing brain are mainly produced by the actions of isoform DS-epi2 and play crucial roles in postnatal development |
715134 |
| 5.1.3.19 | physiological function |
the enzyme converts chondroitin sulfate (CS) to a CS/dermatan sulfate (DS) hybrid chain, which is structurally and conformationally richer than CS, favouring interaction with matrix proteins and growth factors |
749120 |
| 5.1.3.19 | physiological function |
the enzyme converts chondroitin sulfate (CS) to a CS/dermatan sulfate (DS) hybrid chain, which is structurally and conformationally richer than CS, favouring interaction with matrix proteins and growth factors. Xenopus Dse is essential for the migration of neural crest cells by allowing cell surface CS/DS proteoglycans to adhere to fibronectin |
749120 |
| 5.1.3.19 | physiological function |
the enzyme is important in human development and extracellular matrix maintenance |
727608 |
