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EC Number General Information Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 3.6.4.7physiological function the peroxisomal matrix protein import is facilitated by soluble receptor molecules which cycle between cytosol and the peroxisomal membrane. At the end of the receptor cycle, the import receptors are exported back to the cytosol in an ATP-dependent manner catalyzed by a complex of Pex1p and Pex6p 734571
Display the word mapDisplay the reaction diagram Show all sequences 3.6.4.7physiological function the peroxisomal proteins Pex1 and Pex6 complex fuels essential protein transport across peroxisomal membranes. ATP hydrolysis results in a pumping motion of the complex, suggesting that Pex1/6 function involves substrate translocation through its central channel. ATPase activity of Pex6 D2 domains drive conformational changes, Pex1/6 movements during ATP binding and hydrolysis, overview 734752
Display the word mapDisplay the reaction diagram Show all sequences 3.6.4.7physiological function the Pex1/Pex6 complex dislocates and recycles the transport receptor Pex5 from the peroxisomal membrane during peroxisomal protein import 756799
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