Any feedback?
Please rate this page
(search_result.php)
(0/150)

BRENDA support

Refine search

Search Expression

show results
Don't show organism specific information (fast!)
Search organism in taxonomic tree (slow, choose "exact" as search mode, e.g. "mammalia" for rat,human,monkey,...)
(Not possible to combine with the first option)
Refine your search

Search term:

Results 1 - 7 of 7
EC Number Expression Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 7.2.2.8down copper transporter ATP7A protein expression is significantly reduced in blood vessels from type 1 diabetes mellitus mice -, 733703
Display the word mapDisplay the reaction diagram Show all sequences 7.2.2.8more copper has a direct influence on Atp7a protein expression independent of changes in mRNA levels 733059
Display the word mapDisplay the reaction diagram Show all sequences 7.2.2.8up an increase in the external copper concentration induces the enzyme -, 720396
Display the word mapDisplay the reaction diagram Show all sequences 7.2.2.8up Atp7a expression is upregulated by iron chelation and copper loading. Recombinant Atp7a protein expression is induced more strongly than mRNA in the duodenum of iron-deprived rats, Atp7a expression is upregulated by iron chelation and copper loading, iron chelation increases Atp7a mRNA expression by 1.6fold, but has little effect on protein levels 733059
Display the word mapDisplay the reaction diagram Show all sequences 7.2.2.8up insulin treatment, but not high glucose, increases enzyme ATP7A expression in vascular smooth muscles cells -, 733703
Display the word mapDisplay the reaction diagram Show all sequences 7.2.2.8up Sulfolobus responds to exposure to a sublethal copper excess by the transient active transcription of the copA gene. The copA transcript reaches a peak 1 h after treatment, corresponding to approximately 35fold the uninduced level. Thereafter, the transcript level decreases until a steady-state level of 2-3fold induction is reached in the following 16 h. In cells cultured for several generations in the presence of 0.75 mM copper, the amount of copA transcript is maintained at 2-3fold the uninduced level, indicating that its rate of expression is maintained constant during longterm exposures, provided the concentration of copper do not change -, 724167
Display the word mapDisplay the reaction diagram Show all sequences 7.2.2.8up the copA gene is expressed at basal levels in untreated cells of both strain PBL2025 and strain PBL2050. After copper stress, the level of copA transcript increases approximately 30fold. The gene Sso2652 (copR) of the Sulfolobus solfataricus genome encodes a transcriptional activator of the copper-transporting ATPase CopA gene. The CopR protein is a copper-responsive regulators -, 725904
Results 1 - 7 of 7