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5.1.1.8
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live attenuated Salmonella typhimurium (ST) vector constitutively expressing heterologous Brucella abortus S19 PrpA protein (ST-PrpA) is inoculated in BALB/c mice. No aggravation of morbidity is observed upon mice inoculation of ST-PrpA. Immunized mice show significantly quicker anti-Salmonella IgG responses as compared to ST only immunization, and an increase interleukin-4 production evident in in vitro pulsed mice splenocytes, splenocytes proliferative profiles and lymphocyte population evaluation, overview
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748663
5.1.1.8
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the enzyme is strongly induced by cis-4-hydroxy-D-proline, moderately by trans-4-hydroxy-L-proline
728328
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