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4.6.1.14
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during differentiation of bloodstream to insect stage (procyclic), translation GPI-phospholipase C polypeptide mRNA ceases within 8 h of initiating transformation. Reduction of GPI-PLCp in early-stage procyclics is linked to parasite replication
708444
4.6.1.14
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expression of GPI-phospholipase C polypeptide in the parasite is restricted to the bloodstream form. Nascent procyclics contain 400fold more GPI-phospholipase C polypeptide than established insect stage. GPI-PLCp is retained in strains that fail to replicate after differentiation of the bloodstream to the procyclic form
708444
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