EC Number   |
Expression |
Reference |
|---|
   3.5.1.28 | more |
after 1 h of exposure to DC-159a and sitafloxacin, there is no significant increase in the expression of LytA |
711759 |
| 3.5.1.28 | more |
N-acetylmuramoyl-L-alanine amidase is constitutively expressed during infection of cultured human microvascular endothelial cells at the levels of both mRNA transcript and encoded protein |
-, 752896 |
| 3.5.1.28 | more |
the transcription of PGRP-S4 is influenced differentially in different tissues, and the midgut responds to bacterial challenges most strongly |
753816 |
| 3.5.1.28 | up |
after 2 h of exposure to twice the minimum inhibitory concentration, DC-159a increases the expression level of LytA by up to 3.6fold relative to the no drug control. Sitafloxacin induces expression of LytA by up to 4.6fold in S. pneumoniae strain R6 with 2 h of exposure to the minimum inhibitory concentration. Garenoxacin causes a less significant increase in LytA (up to 2.7fold at 2 h) than DC-159a and sitafloxacin |
711759 |
| 3.5.1.28 | up |
LytA is activated at the end of the lytic cycle, LytA is activated by the holing-induced membrane disruption |
712286 |
| 3.5.1.28 | up |
the enzyme expression level is significantly induced by bacterial challenges in the midgut. Six hours after feeding, Staphylococcus aureus stimulates the PGRP-S4 level to over 150fold, and the level climbs even higher to 600fold at 12 h |
753816 |
