EC Number   |
Expression |
Reference |
|---|
   3.4.24.7 | down |
both the MMP-1 and TIMP-1 mRNA expression level are dramatically downregulated by baicalin |
708406 |
| 3.4.24.7 | down |
curcumin at the concentration of 2.5-5 mg/ml specifically downregulates MMP-1 mRNA in BT-483 and MDA-MB-231 breast cancer cell lines. Cell growth and proliferation is inhibited in presence of curcumin, overview |
710246 |
| 3.4.24.7 | down |
curcumin, a potent inhibitor for AP-1, or simvastatin inhibit the expression of MMP-1. Suppression of c-Jun expression by RNA interference significantly inhibits MMP-1 expression |
709234 |
| 3.4.24.7 | down |
dexamethasone suppression of MMP-1 gene expression |
709370 |
| 3.4.24.7 | down |
dexamethasone, and less potent also interleukin-1Ra and TNF, decrease levels of pro-MMP-1 |
707312 |
| 3.4.24.7 | down |
expression of MMP-1 in cartilages and synovial tissues is suppressed by the treatment of curcumin and indomethacin. Production of MMP-1 is inhibited by curcumin in tumor necrosis factor-alpha-stimulated rheumatoid arthritis fibroblast-like synoviocytes and chondrocytes in a dose-dependent manner putatively through the inhibition of PKCdelta and the JNK/c-Jun signaling pathway, overview |
709685 |
| 3.4.24.7 | down |
fucoidan treatment significantly inhibits the expression of MMP-1 |
709591 |
| 3.4.24.7 | down |
increased MMP1 expression in JJ cell line can be inhibited by siRNA directed at HIF-1a or CXCR4, the CXCR4 inhibitor AMD3100, as well as with ERK inhibitor U0126 and ERK siRNA |
709913 |
| 3.4.24.7 | down |
inhibition of MMP-1 expression by extracts of Kaempferia pandurata, overview |
709482 |
| 3.4.24.7 | down |
inhibititory effects of potent antioxidant astaxanthin on the MMP-1 induction by UV-A irradiation, overview |
709289 |
