EC Number   |
Expression |
Reference |
|---|
   3.4.24.22 | down |
MMP-10 expression is downregulated with age, overview |
708594 |
| 3.4.24.22 | down |
PD98059 and SP600125, ERK and JNK inhibitors, respectively, repress VEGF-induced MMP-10 expression to mRNA expression levels lower than the basal expression of MMP-10 |
709245 |
| 3.4.24.22 | down |
stromelysin-2 is slightly downregulated in obese adipose tissue compared to non-obese adipose tissue |
707379 |
| 3.4.24.22 | more |
strong positive correlation between tumor Mmp10 expression and metastatic behavior in many human tumor types |
-, 735049 |
| 3.4.24.22 | up |
enhanced collagen degradation, in case of epithelial-to-mesenchymal transition stimulated by transforming growth factor-beta as well as epidermal growth factor receptor, is coupled to a significant increase in matrix metalloproteinase MMP-10 expression and is involved a proteolytic axis composed of plasmin, MMP-10, and MMP-1, ec 3.4.24.7 |
707982 |
| 3.4.24.22 | up |
high expression of MMP-10 is frequently observed and is significantly correlated with the invasiveness and metastasis in head and neck squamous cell carcinoma cases |
718291 |
| 3.4.24.22 | up |
increased MMP-10 levels in severe sepsis |
708234 |
| 3.4.24.22 | up |
loss or knockdown of transcription factor CHF1/Hey2 in vascular smooth muscle cells leads to increased expression and activity of MMP10 at baseline. CHF1/Hey2 regulates MMP10 expression through multiple E boxes |
717202 |
| 3.4.24.22 | up |
Mmp10 is overexpressed in lung tumors induced by either the smoke carcinogen urethane or oncogenic Kras |
718298 |
| 3.4.24.22 | up |
neuronal MMP-10 is upregulated after stroke in brain in the infarcted tissue compared to healthy control areas, overview |
709700 |
