EC Number   |
Expression |
Reference |
|---|
   2.7.11.26 | down |
after lactacystin treatment, the total level of GSK-3beta does not change while the Ser-9-phosphorylated GSK-3beta (inactive form) decreases, especially at 72 h |
705898 |
| 2.7.11.26 | down |
LiCl and BIO also reduce the expression of GSK3beta |
705282 |
| 2.7.11.26 | down |
the reduction of tau phosphorylation by treatment with 100 nM leptin is mimicked by the downregulation of GSK-3beta |
705916 |
| 2.7.11.26 | more |
administration of insulin or TDZD-8 to diabetic rats does not modify the total GSK-3beta mRNA levels |
703382 |
| 2.7.11.26 | up |
5-azacytidine treatment (0.005 mM for 24 h) causes significant up-regulation of GSK-3beta whereas it stimulates GSK-3alpha expression only modestly |
704607 |
| 2.7.11.26 | up |
GSK-3beta levels are elevated by about 80% in APP transgenic neuronal cultures |
705285 |
| 2.7.11.26 | up |
isoform TTBK1 is upregulated in the frontal cortex of patients with Alzheimer's disease |
761031 |
| 2.7.11.26 | up |
knocking out miR-369 in Alzheimer's disease mice promotes hyperphosphorylation of tau and upregulates enzyme expression |
761120 |
