   2.1.1.90 | more |
methanol-specific methyltransferase MT1 isozymes are encoded by three operons mtaCB1, mtaCB2, and mtaCB3. When expressed from the strong PmtaC1 or PmtaC2 promoter, each of the MtaC and MtaB proteins supports growth and methane production at wild-type levels. In contrast, all mtaCB operons exhibit poorer growth and lower rates of methane production when PmtaC3 controlls their expression. All combinations of MtaC, MtaB, and MtaA can form functional methyltransferase MT1/MT2 complexes. Variations in enzyme activity correlate with differences in protein abundance. The mtaCBA transcripts show different stabilities, which are strongly influenced by the growth substrate |
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