EC Number   |
Expression |
Reference |
|---|
    1.3.1.3 | down |
chenodeoxycholic acid markedly represses AKR1D1 expression in vitro in human hepatoma Hep-G2 cells, regulation occurs through the mitogen-activated protein kinases/c-Jun Nterminal kinases (MAPK/JNK) signaling pathway |
763613 |
| 1.3.1.3 | down |
chenodeoxycholic acid markedly represses AKR1D1 expression, regulation occurs through the mitogen-activated protein kinases/c-Jun Nterminal kinases (MAPK/JNK) signaling pathway |
763613 |
| 1.3.1.3 | down |
presence of chenodeoxycholic acid reduces transcript abundance in H4iiE cell and promoter activity in HepG2 cells |
725633 |
| 1.3.1.3 | up |
cholic acid significantly upregulates AKR1D1 expression in HepG2 cells, regulation occurs through the mitogen-activated protein kinases/c-Jun Nterminal kinases (MAPK/JNK) signaling pathway |
763613 |
| 1.3.1.3 | up |
cholic acid significantly upregulates AKR1D1 expression, regulation occurs through the mitogen-activated protein kinases/c-Jun Nterminal kinases (MAPK/JNK) signaling pathway |
763613 |
| 1.3.1.3 | up |
treatment of cells with proteasomal inhibitor, MG-132 increases expression of splice variants AKR1D1-001 and AKR1D1-006 |
763367 |
