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EC Number	Expression	Commentary	Reference
1.2.4.1	down	the activity of pyruvate dehydrogenase is reduced in diabetic rats. Thiamine ameliorates diabetes-induced PDH inhibition by suppressing the increased expression of the O-glycosylated protein	712851
1.2.4.1	more	high glucose loads do not alter the level of PDH mRNA expressions in cardiac fibroblasts	712851
1.2.4.1	up	the O-glycosylated PDH protein is markedly increased in cardiac fibroblasts exposed to high glucose	712851

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Release 2023.1 (January 2023)