EC Number   |
Expression |
Reference |
|---|
    1.14.15.15 | up |
astrocyte-restricted upregulation of Cyp27a1 due to to differential expression of transcriptional co-activators, increase of enzyme mRNA and protein levels in treated astrocytes is paralleled by transactivation of the proximal Cyp27a1 promoter in transfected astrocytes |
705935 |
| 1.14.15.15 | up |
dexamethasone increases CYP27A1-mediated enzyme activity in HepG2 cells by CYP27A1 promoter activity more than 4fold as compared with untreated cells, mediated by glucocorticoid receptor alpha, glucocorticoid receptor alpha-antagonist mifepristone almost completely abolishes the dexamethasone-induced effect on the CYP27A1 promoter activity |
702408 |
| 1.14.15.15 | up |
in vivo, in a high-salt administration experiment, male and female Dahl salt-sensitive rats become hypertensive after 4 weeks on a high-NaCl diet, their plasma marinobufagenin levels double, and adrenocortical CYP27A1 mRNA and protein increase 1.6fold and 2.0fold, respectively |
735969 |
| 1.14.15.15 | up |
ritonavir increases CYP27 expression in in differentiated THP-1 macrophages, but not in undifferentiated monocytes |
703582 |
