   1.1.1.324 | up |
the enzyme expression is activated by transcription factor BIS3, i.e. BHLH iridoid synthesis 3, a basic helix-loop-helix (bHLH) transcription factor and key regulators of plant specialized metabolites, including terpenoid indole alkaloids, in Catharanthus roseus plants. BIS3 is clustered with BIS2 and BIS1 in a bHLH gene cluster. Similar to the iridoid pathway genes, BIS3 is highly expressed in roots and induced by methyl jasmonate. Transactivation of the promoters is abolished when BIS3 is converted to a dominant repressor by fusing with the ERF-associated amphiphilic repression (EAR) sequence (BIS3-SRDX) |
763575 |
