EC Number   |
Expression  |
Reference |
|---|
   3.4.24.B6 | down |
loss and siRNA-mediated silencing of Runx2 in ameloblast-lineage cells decreases ODAM expression, resulting in downregulation of MMP-20 expression |
712555 |
| 3.4.24.B6 | more |
Mmp20 expression levels must be within a specific range for normal enamel development to occur. Creation of a normally thick enamel layer may occur over a wider range of Mmp20 expression levels, but acquisition of normal enamel hardness has a narrower range |
735135 |
| 3.4.24.B6 | up |
increased expression of ODAM and Runx2 augments MMP-20 expression, and both TGF-beta1 and BMP-2 up-regulate Runx2 expression. TGF-beta1 promotes MMP-20 expression in ameloblasts |
712555 |
| 3.4.24.B6 | up |
transforming growth factor-beta1, TGF-beta1, prominently induces MMP20 expression in ameloblast-lineage cells |
710860 |
