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EC Number Expression Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.53up incubation of human retinal microvascular endothelial cells with vascular endothelial growth factor results in 1.6fold increased activity of calpain 2 at 24 h 709652
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.53up m-calpain activation occurs during reperfusion, but only after intracellular pH normalization, and is not prevented by inhibiting its translocation during ischemia with methyl-beta-cyclodextrin 709566
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.53up p38 MAPK and JNK are required to stimulate m-calpain activity when TRPM7 is overexpressed, TRPM7-mediated activation of m-calpain is not dependent on the nature of the divalent conducted by the channel 709540
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