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EC Number
Expression
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1.14.17.1
up
forced expression of Trim11 with Phox2b specifically increases mRNA levels of dopamine beta-hydroxylase gene in primary avian neural crest stem cell culture compared to cultures where only Phox2b is forced expressed
702012
1.14.17.1
up
forskolin, dexamethasone, ionomycin, and 17-beta-estradiol all induce a significant increase in DBH promoter activity, the most significant 15.8fold upregulation of DBH transcription is observed in forskolin-treated cells The forskolin-induced DBH upregulation in SK-N-BE(2) cells is attenuated by alpha-Syn. CRE-mediated transcriptional regulation of tyrosine hydroxylase and enzyme DBH plays a crucial role in stress response
744851
1.14.17.1
up
transfection of 0.1 to 5 microg of cDNAs of Phox2a or Phox2b significantly increases mRNA and protein levels of DBH (up to 47%) in a concentration-dependent manner. Simultanoeus transfection with both Phox2a and Phox2b does not further increase mRNA and protein levels of DBH
705254
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