EC Number   |
BRENDA No. |
Title |
Journal |
Volume |
Pages |
Year |
Organism |
PubMed ID |
|---|
   3.4.24.82 | 754392 |
A highly selective hydantoin inhibitor of aggrecanase-1 and aggrecanase-2 with a low projected human dose |
J. Med. Chem. |
60 |
5933-5939 |
2017 |
Homo sapiens |
28613895 |
| 3.4.24.82 | 754958 |
Cleavage of fibulin-2 by the aggrecanases ADAMTS-4 and ADAMTS-5 contributes to the tumorigenic potential of breast cancer cells |
Oncotarget |
8 |
13716-13729 |
2017 |
Homo sapiens |
28099917 |
| 3.4.24.82 | 755457 |
Critical role of ADAMTS-4 in the development of sporadic aortic aneurysm and dissection in mice |
Sci. Rep. |
7 |
12351 |
2017 |
Mus musculus |
28955046 |
| 3.4.24.82 | 752659 |
Development of human neutralizing antibody to ADAMTS4 (aggrecanase-1) and ADAMTS5 (aggrecanase-2) |
Biochem. Biophys. Res. Commun. |
469 |
62-69 |
2016 |
Homo sapiens |
26612259 |
| 3.4.24.82 | 754633 |
Purification and activity determination of ADAMTS-4 and ADAMTS-5 and their domain deleted mutants |
Methods Mol. Biol. |
2043 |
75-91 |
2020 |
Homo sapiens |
31463904 |
| 3.4.24.82 | 752411 |
The metalloprotease ADAMTS4 generates N-truncated A?4-x species and marks oligodendrocytes as a source of amyloidogenic peptides in Alzheimers disease |
Acta Neuropathol. |
137 |
239-257 |
2019 |
Mus musculus |
30426203 |
| 3.4.24.82 | 638966 |
A microplate assay specific for the enzyme aggrecanase |
Anal. Biochem. |
314 |
260-265 |
2003 |
Bos taurus |
12654313 |
| 3.4.24.82 | 638964 |
Activation of the proteolytic activity of ADAMTS4 (aggrecanase-1) by C-terminal truncation |
J. Biol. Chem. |
277 |
11034-11041 |
2002 |
Homo sapiens |
11796708 |
| 3.4.24.82 | 638964 |
Activation of the proteolytic activity of ADAMTS4 (aggrecanase-1) by C-terminal truncation |
J. Biol. Chem. |
277 |
11034-11041 |
2002 |
Sus scrofa |
11796708 |
| 3.4.24.82 | 668117 |
ADAMTS-1 and -4 are up-regulated following transient middle cerebral artery occlusion in the rat and their expression is modulated by TNF in cultured astrocytes |
Brain Res. |
1088 |
19-30 |
2006 |
Homo sapiens |
16630594 |
