EC Number |
Title |
Organism |
---|
3.4.23.46 | 2-Substituted-thio-N-(4-substituted-thiazol/1H-imidazol-2-yl)acetamides as BACE1 inhibitors Synthesis, biological evaluation and docking studies |
Homo sapiens |
3.4.23.46 | A comparative molecular dynamics study on BACE1 and BACE2 flap flexibility |
Homo sapiens |
3.4.23.46 | Application of BACE1 immobilized enzyme reactor for the characterization of multifunctional alkaloids from Corydalis cava (Fumariaceae) as Alzheimers disease targets |
Homo sapiens |
3.4.23.46 | Computational analysis of BACE1-ligand complex crystal structures and linear discriminant analysis for identification of BACE1 inhibitors with anti P-glycoprotein binding property |
Homo sapiens |
3.4.23.46 | Computational insights into beta-site amyloid precursor protein enzyme 1 (BACE1) inhibition by tanshinones and salvianolic acids from Salvia miltiorrhiza via molecular docking simulations |
Homo sapiens |
3.4.23.46 | Design and synthesis of bicyclic acetals as beta secretase (BACE1) inhibitors |
Homo sapiens |
3.4.23.46 | Design of potent and highly selective inhibitors for human beta-secretase 2 (memapsin 1), a target for type 2 diabetes |
Homo sapiens |
3.4.23.46 | Design, synthesis, X-ray studies, and biological evaluation of novel BACE1 inhibitors with bicyclic isoxazoline carboxamides as the P3 ligand |
Homo sapiens |
3.4.23.46 | Discovery of imidazopyridines containing isoindoline-1,3-dione framework as a new class of BACE1 inhibitors Design, synthesis and SAR analysis |
Homo sapiens |
3.4.23.46 | Discovery of S3-truncated, C-6 heteroaryl substituted aminothiazine beta-site APP cleaving enzyme-1 (BACE1) inhibitors |
Mus musculus |