EC Number   |
Title |
Organism |
|---|
   3.4.23.45 | A comparative molecular dynamics study on BACE1 and BACE2 flap flexibility |
Homo sapiens |
| 3.4.23.45 | BACE2 distribution in major brain cell types and identification of novel substrates |
Mus musculus |
| 3.4.23.45 | BACE2, a conditional beta-secretase, contributes to Alzheimer's disease pathogenesis |
Mus musculus |
| 3.4.23.45 | Design of potent and highly selective inhibitors for human beta-secretase 2 (memapsin 1), a target for type 2 diabetes |
Homo sapiens |
| 3.4.23.45 | Highly selective and potent human beta-secretase 2 (BACE2) inhibitors against type 2 diabetes design, synthesis, X-ray structure and structure-activity relationship studies |
Homo sapiens |
| 3.4.23.45 | Structure-based design of selective beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors targeting the flap to gain selectivity over BACE2 |
Homo sapiens |
| 3.4.23.45 | A new aspartyl protease on 21q22.3, BACE2, is highly similar to Alzheimer's amyloid precursor protein beta-secretase |
Homo sapiens |
| 3.4.23.45 | A non-amyloidogenic function of BACE-2 in the secretory pathway |
Homo sapiens |
| 3.4.23.45 | Altered beta-secretase enzyme kinetics and levels of both BACE1 and BACE2 in the Alzheimers disease brain |
Homo sapiens |
| 3.4.23.45 | Altered beta-secretase enzyme kinetics and levels of both BACE1 and BACE2 in the Alzheimers disease brain |
Rattus norvegicus |
