EC Number   |
BRENDA No. |
Title |
Journal |
Volume |
Pages |
Year |
Organism |
PubMed ID |
|---|
   3.4.21.61 | 753959 |
New aromatic compounds from the fruiting body of Sparassis crispa (Wulf.) and their inhibitory activities on proprotein convertase subtilisin/kexin type 9 mRNA expression |
J. Agric. Food Chem. |
65 |
6152-6157 |
2017 |
Homo sapiens |
28689410 |
| 3.4.21.61 | 753290 |
Novel insights into the mechanisms regulating pro-atrial natriuretic peptide cleavage in the heart and blood pressure regulation proprotein convertase subtilisin/kexin 6 is the corin activating enzyme |
Circ. Res. |
118 |
196-198 |
2016 |
Homo sapiens |
26838312 |
| 3.4.21.61 | 754945 |
Proprotein convertase subtilisin/kexin type 6 activates the extracellular signal-regulated kinase 1/2 and Wnt family member 3A pathways and promotes in vitro proliferation, migration and invasion of breast cancer MDA-MB-231 cells |
Oncol. Lett. |
16 |
145-150 |
2018 |
Homo sapiens |
29928395 |
| 3.4.21.61 | 754760 |
Proprotein convertase subtilisin/kexin type 6 promotes in vitro proliferation, migration and inflammatory cytokine secretion of synovial fibroblast-like cells from rheumatoid arthritis via nuclear-kappaB, signal transducer and activator of transcription 3 and activator of transcription 3 and extracellular signal regulated 1/2 pathways |
Mol. Med. Rep. |
16 |
8477-8484 |
2017 |
Homo sapiens |
28944919 |
| 3.4.21.61 | 650220 |
2.4 A resolution crystal structure of the prototypical hormone-processing protease Kex2 in complex with an Ala-Lys-Arg boronic acid inhibitor |
Biochemistry |
42 |
6709-6718 |
2003 |
Saccharomyces cerevisiae |
12779325 |
| 3.4.21.61 | 717860 |
A novel domain interaction regulates secretion of proprotein convertase subtilisin/kexin type 9 |
J. Biol. Chem. |
286 |
43054-43061 |
2011 |
Homo sapiens |
22027821 |
| 3.4.21.61 | 717860 |
A novel domain interaction regulates secretion of proprotein convertase subtilisin/kexin type 9 |
J. Biol. Chem. |
286 |
43054-43061 |
2011 |
Mus musculus |
22027821 |
| 3.4.21.61 | 686335 |
A novel splicing variant of proprotein convertase subtilisin/kexin type 9 |
DNA Cell Biol. |
27 |
183-189 |
2008 |
Homo sapiens |
18052825 |
| 3.4.21.61 | 709095 |
A proprotein convertase subtilisin-like/kexin type 9 (PCSK9) C-terminal domain antibody antigen-binding fragment inhibits PCSK9 internalization and restores low density lipoprotein uptake |
J. Biol. Chem. |
285 |
12882-12891 |
2010 |
Homo sapiens |
20172854 |
| 3.4.21.61 | 710427 |
A proprotein convertase subtilisin/kexin type 9 neutralizing antibody reduces serum cholesterol in mice and nonhuman primates |
Proc. Natl. Acad. Sci. USA |
106 |
9820-9825 |
2009 |
Macaca fascicularis |
19443683 |
