EC Number   |
Title |
Organism |
|---|
   3.4.21.47 | Bacterial killing by complement requires membrane attack complex formation via surface-bound C5 convertases |
Homo sapiens |
| 3.4.21.47 | C5 convertase blockade in membranoproliferative glomerulonephritis a single-arm clinical trial |
Homo sapiens |
| 3.4.21.47 | Functional characterization of alternative and classical pathway C3/C5 convertase activity and inhibition using purified models |
Homo sapiens |
| 3.4.21.47 | Molecular insights into the surface-specific arrangement of complement C5 convertase enzymes |
Homo sapiens |
| 3.4.21.47 | Neisseria heparin binding antigen is targeted by the human alternative pathway C3-convertase |
Homo sapiens |
| 3.4.21.47 | The human complement receptor type 2 (CR2)/CR1 fusion protein TT32, a novel targeted inhibitor of the classical and alternative pathway C3 convertases, prevents arthritis in active immunization and passive transfer mouse models |
Homo sapiens |
| 3.4.21.47 | 3D structure of the C3bB complex provides insights into the activation and regulation of the complement alternative pathway convertase |
Homo sapiens |
| 3.4.21.47 | A conserved element in the serine protease domain of complement factor B |
Homo sapiens |
| 3.4.21.47 | A novel approach to preventing the hemolysis of paroxysmal nocturnal hemoglobinuria: both complement-mediated cytolysis and C3 deposition are blocked by a monoclonal antibody specific for the alternative pathway of complement |
Homo sapiens |
| 3.4.21.47 | Access to the complement factor B scissile bond is facilitated by association of factor B with C3b protein |
Homo sapiens |
