EC Number   |
BRENDA No. |
Title |
Journal |
Volume |
Pages |
Year |
Organism  |
PubMed ID |
|---|
   3.4.21.46 | 754401 |
Design, synthesis, and preclinical characterization of selective factor D inhibitors targeting the alternative complement pathway |
J. Med. Chem. |
62 |
4656-4668 |
2019 |
Homo sapiens |
30995036 |
| 3.4.21.46 | 752372 |
Discovery and design of first benzylamine-based ligands binding to an unlocked conformation of the complement factor D |
ACS Med. Chem. Lett. |
9 |
490-495 |
2018 |
Homo sapiens |
29795765 |
| 3.4.21.46 | 754391 |
Discovery of highly potent and selective small-molecule reversible factor D inhibitors demonstrating alternative complement pathway inhibition in vivo |
J. Med. Chem. |
60 |
5717-5735 |
2017 |
Homo sapiens |
28621538 |
| 3.4.21.46 | 754127 |
Dynamic regulation of platelet-derived growth factor D (PDGF-D) activity and extracellular spatial distribution by matriptase-mediated proteolysis |
J. Biol. Chem. |
290 |
9162-9170 |
2015 |
Homo sapiens |
25678707 |
| 3.4.21.46 | 752876 |
Senescent dermal fibroblasts negatively influence fibroblast extracellular matrix-related gene expression partly via secretion of complement factor D |
Biofactors |
45 |
556-562 |
2019 |
Homo sapiens |
31026383 |
| 3.4.21.46 | 668289 |
Analysis of protein absorbed by LDL column (Liposorber) with special reference to complement component factor D |
Clin. Chim. Acta |
342 |
155-160 |
2004 |
Homo sapiens |
15026276 |
| 3.4.21.46 | 699302 |
Baculovirus is an efficient vector for the transduction of the eye: comparison of baculovirus- and adenovirus-mediated intravitreal vascular endothelial growth factor D gene transfer in the rabbit eye |
J. Gene Med. |
11 |
382-389 |
2009 |
Homo sapiens |
19263462 |
| 3.4.21.46 | 683539 |
Complement factor D, albumin, and immunoglobulin G anti-band 3 protein antibodies mimic serum in promoting rosetting of malaria-infected red blood cells |
Infect. Immun. |
75 |
1771-1777 |
2007 |
Homo sapiens |
17261605 |
| 3.4.21.46 | 36587 |
Crystal structure of a complement factor D mutant expressing enhanced catalytic activity [published erratum appears in J Biol Chem 1995 Dec 29;270(52):31414 |
J. Biol. Chem. |
270 |
24399-24405 |
1995 |
Homo sapiens |
7592653 |
| 3.4.21.46 | 668074 |
Deficient alternative complement pathway activation due to factor D deficiency by 2 novel mutations in the complement factor D gene in a family with meningococcal infections |
Blood |
107 |
4865-4870 |
2006 |
Homo sapiens |
16527897 |
