EC Number   |
BRENDA No. |
Title |
Journal |
Volume |
Pages |
Year |
Organism |
PubMed ID |
|---|
   3.4.17.11 | 753264 |
Characterisation of the carboxypeptidase G2 catalytic site and design of new inhibitors for cancer therapy |
ChemBioChem |
19 |
1959-1968 |
2018 |
Pseudomonas sp. RS-16 |
29968955 |
| 3.4.17.11 | 755292 |
Engineering carboxypeptidase G2 circular permutations for the design of an autoinhibited enzyme |
Protein Eng. Des. Sel. |
30 |
321-331 |
2017 |
Pseudomonas sp. RS-16 |
28160000 |
| 3.4.17.11 | 752914 |
Production of "biobetter" variants of glucarpidase with enhanced enzyme activity |
Biomed. Pharmacother. |
112 |
108725 |
2019 |
Pseudomonas sp. RS-16 |
30970523 |
| 3.4.17.11 | 755301 |
Soluble expression, purification and functional characterisation of carboxypeptidase G2 and its individual domains |
Protein Expr. Purif. |
127 |
44-52 |
2016 |
Pseudomonas sp. RS-16 |
27374188 |
| 3.4.17.11 | 755593 |
TAT-mediated intracellular delivery of carboxypeptidase G2 protects against methotrexate-induced cell death in HepG2 cells |
Toxicol. Appl. Pharmacol. |
346 |
9-18 |
2018 |
Pseudomonas sp. RS-16 |
29574210 |
| 3.4.17.11 | 700491 |
A novel technique to monitor carboxypeptidase G2 expression in suicide gene therapy using (19)F magnetic resonance spectroscopy |
NMR Biomed. |
22 |
561-566 |
2009 |
Homo sapiens |
19259950 |
| 3.4.17.11 | 679268 |
A phase I study of single administration of antibody-directed enzyme prodrug therapy with the recombinant anti-carcinoembryonic antigen antibody-enzyme fusion protein MFECP1 and a bis-iodo phenol mustard prodrug |
Clin. Cancer Res. |
12 |
6509-6516 |
2006 |
Pseudomonas aeruginosa |
17085666 |
| 3.4.17.11 | 697374 |
Attenuated Salmonella targets prodrug activating enzyme carboxypeptidase G2 to mouse melanoma and human breast and colon carcinomas for effective suicide gene therapy |
Clin. Cancer Res. |
14 |
4259-4266 |
2008 |
Pseudomonas sp. |
18594008 |
| 3.4.17.11 | 647246 |
Carboxypeptidase displaying differential velocity in hydrolysis of methotrexate, 5-methyltetrahydrofolic acid, and leucovorin |
J. Bacteriol. |
134 |
506-513 |
1978 |
Flavobacterium sp. |
26657 |
| 3.4.17.11 | 668101 |
Carboxypeptidase G2 rescue in patients with methotrexate intoxication and renal failure |
Br. J. Cancer |
92 |
480-487 |
2005 |
Pseudomonas sp. |
15668713 |
