EC Number |
BRENDA No. |
Title |
Journal |
Volume |
Pages |
Year |
Organism |
PubMed ID |
---|
2.7.7.86 | 761268 |
Cyclic GMP-AMP synthase is essential for cytosolic double-stranded DNA and fowl adenovirus serotype 4 triggered innate immune responses in chickens |
Int. J. Biol. Macromol. |
146 |
497-507 |
2020 |
Gallus gallus |
31923489 |
2.7.7.86 | 761638 |
Cyclic GMP-AMP synthase is the cytosolic sensor of Plasmodium falciparum genomic DNA and activates type I IFN in malaria |
J. Immunol. |
200 |
768-774 |
2018 |
Homo sapiens |
29212905 |
2.7.7.86 | 762288 |
Cyclic GMP-AMP synthase promotes the inflammatory and autophagy responses in Huntington disease |
Proc. Natl. Acad. Sci. USA |
117 |
15989-15999 |
2020 |
Mus musculus |
32581130 |
2.7.7.86 | 762288 |
Cyclic GMP-AMP synthase promotes the inflammatory and autophagy responses in Huntington disease |
Proc. Natl. Acad. Sci. USA |
117 |
15989-15999 |
2020 |
Homo sapiens |
32581130 |
2.7.7.86 | 762288 |
Cyclic GMP-AMP synthase promotes the inflammatory and autophagy responses in Huntington disease |
Proc. Natl. Acad. Sci. USA |
117 |
15989-15999 |
2020 |
Mus musculus C57BL/6J |
32581130 |
2.7.7.86 | 761723 |
Discovery of small-molecule cyclic GMP-AMP synthase inhibitors |
J. Org. Chem. |
85 |
1579-1600 |
2020 |
Homo sapiens |
31829590 |
2.7.7.86 | 761514 |
Dysfunctional telomeres trigger cellular senescence mediated by cyclic GMP-AMP synthase |
J. Biol. Chem. |
295 |
11144-11160 |
2020 |
Homo sapiens |
32540968 |
2.7.7.86 | 761597 |
In silico screening-based discovery of novel inhibitors of human cyclic GMP-AMP synthase a cross-validation study of molecular docking and experimental testing |
J. Chem. Inf. Model. |
60 |
3265-3276 |
2020 |
Homo sapiens |
32459092 |
2.7.7.86 | 761781 |
Small molecule inhibition of cyclic GMP-AMP synthase ameliorates sepsis-induced cardiac dysfunction in mice |
Life Sci. |
260 |
118315 |
2020 |
Mus musculus |
32835697 |
2.7.7.86 | 762338 |
The catalytic mechanism of cyclic GMP-AMP synthase (cGAS) and implications for innate immunity and inhibition |
Protein Sci. |
26 |
2367-2380 |
2017 |
Homo sapiens |
28940468 |