EC Number |
Title |
Organism |
---|
2.7.11.2 | Astrocytic pyruvate dehydrogenase kinase-2 is involved in hypothalamic inflammation in mouse models of diabetes |
Mus musculus |
2.7.11.2 | Development of dihydroxyphenyl sulfonylisoindoline derivatives as liver-targeting pyruvate dehydrogenase kinase inhibitors |
Homo sapiens |
2.7.11.2 | Development of dual inhibitors targeting pyruvate dehydrogenase kinases and human lactate dehydrogenase A High-throughput virtual screening, synthesis and biological validation |
Homo sapiens |
2.7.11.2 | Discovery of novel pyruvate dehydrogenase kinases inhibitors by screening of an in-house small molecule library for anti-lung cancer therapeutics |
Homo sapiens |
2.7.11.2 | Effect of pH on the structure and function of pyruvate dehydrogenase kinase 3 Combined spectroscopic and MD simulation studies |
Homo sapiens |
2.7.11.2 | Identification of high-affinity inhibitors of pyruvate dehydrogenase kinase-3 towards therapeutic management of cancer |
Homo sapiens |
2.7.11.2 | Identification of novel pyruvate dehydrogenase kinase 1 (PDK1) inhibitors by kinase activity-based high-throughput screening for anticancer therapeutics |
Homo sapiens |
2.7.11.2 | In vitro cytotoxicity screening to identify novel anti-osteosarcoma therapeutics targeting pyruvate dehydrogenase kinase 2 |
Homo sapiens |
2.7.11.2 | Pyruvate dehydrogenase kinase 1 interferes with glucose metabolism reprogramming and mitochondrial quality control to aggravate stress damage in cancer |
Homo sapiens |
2.7.11.2 | Pyruvate dehydrogenase kinase 4 mediates lipogenesis and contributes to the pathogenesis of nonalcoholic steatohepatitis |
Homo sapiens |