EC Number   |
BRENDA No. |
Title |
Journal |
Volume |
Pages |
Year |
Organism |
PubMed ID |
|---|
   2.1.1.100 | 757231 |
Isoprenylcysteine carboxy methyltransferase (ICMT) is associated with tumor aggressiveness and its expression is controlled by the p53 tumor suppressor |
J. Biol. Chem. |
294 |
5060-5073 |
2019 |
Homo sapiens |
30655292 |
| 2.1.1.100 | 757874 |
Isoprenylcysteine carboxylmethyltransferase function is essential for RAB4A-mediated integrin beta3 recycling, cell migration and cancer metastasis |
Oncogene |
36 |
5757-5767 |
2017 |
Homo sapiens |
28604748 |
| 2.1.1.100 | 755981 |
Isoprenylcysteine carboxylmethyltransferase is associated with nasopharyngeal carcinoma chemoresistance and Ras activation |
Biochem. Biophys. Res. Commun. |
516 |
784-789 |
2019 |
Homo sapiens |
31253403 |
| 2.1.1.100 | 757873 |
Isoprenylcysteine carboxylmethyltransferase is critical for malignant transformation and tumor maintenance by all RAS isoforms |
Oncogene |
36 |
3934-3942 |
2017 |
Homo sapiens |
28192404 |
| 2.1.1.100 | 755969 |
Isoprenylcysteine carboxylmethyltransferase regulates ovarian cancer cell response to chemotherapy and Ras activation |
Biochem. Biophys. Res. Commun. |
501 |
556-562 |
2018 |
Homo sapiens |
29746868 |
| 2.1.1.100 | 757563 |
Non-substrate based, small molecule inhibitors of the human isoprenylcysteine carboxyl methyltransferase |
MedChemComm |
7 |
1016-1021 |
2016 |
Homo sapiens |
27547295 |
| 2.1.1.100 | 676786 |
A small-molecule inhibitor of isoprenylcysteine carboxyl methyltransferase with antitumor activity in cancer cells |
Proc. Natl. Acad. Sci. USA |
102 |
4336-4341 |
2005 |
Homo sapiens |
15784746 |
| 2.1.1.100 | 719091 |
Amide-modified prenylcysteine based Icmt inhibitors: Structure-activity relationships, kinetic analysis and cellular characterization |
Bioorg. Med. Chem. |
20 |
283-295 |
2012 |
Homo sapiens |
22142613 |
| 2.1.1.100 | 672603 |
Amide-substituted farnesylcysteine analogs as inhibitors of human isoprenylcysteine carboxyl methyltransferase |
Bioorg. Med. Chem. Lett. |
16 |
4420-4423 |
2006 |
Homo sapiens |
16777414 |
| 2.1.1.100 | 720184 |
Amino derivatives of indole as potent inhibitors of isoprenylcysteine carboxyl methyltransferase |
J. Med. Chem. |
53 |
6838-6850 |
2010 |
Homo sapiens |
20809634 |
