EC Number |
BRENDA No. |
Title |
Journal |
Volume |
Pages |
Year |
Organism |
PubMed ID |
---|
1.14.19.17 | 744398 |
Dihydroceramide desaturase 1, the gatekeeper of ceramide induced lipotoxicity |
Biochim. Biophys. Acta |
1851 |
40-50 |
2015 |
Chlorocebus aethiops |
25283058 |
1.14.19.17 | 744398 |
Dihydroceramide desaturase 1, the gatekeeper of ceramide induced lipotoxicity |
Biochim. Biophys. Acta |
1851 |
40-50 |
2015 |
Mus musculus |
25283058 |
1.14.19.17 | 744398 |
Dihydroceramide desaturase 1, the gatekeeper of ceramide induced lipotoxicity |
Biochim. Biophys. Acta |
1851 |
40-50 |
2015 |
Homo sapiens |
25283058 |
1.14.19.17 | 744398 |
Dihydroceramide desaturase 1, the gatekeeper of ceramide induced lipotoxicity |
Biochim. Biophys. Acta |
1851 |
40-50 |
2015 |
Drosophila melanogaster |
25283058 |
1.14.19.17 | 744418 |
Dihydroceramide desaturase inhibitors induce autophagy via dihydroceramide-dependent and independent mechanisms |
Biochim. Biophys. Acta |
1861 |
264-275 |
2017 |
Homo sapiens |
27894925 |
1.14.19.17 | 744061 |
Dihydroceramide-desaturase-1-mediated caspase 9 activation through ceramide plays a pivotal role in palmitic acid-induced HepG2 cell apoptosis |
Apoptosis |
21 |
1033-1044 |
2016 |
Homo sapiens |
27364952 |
1.14.19.17 | 745527 |
From sphingosine kinase to dihydroceramide desaturase a structure-activity relationship (SAR) study of the enzyme inhibitory and anticancer activity of 4-((4-(4-chlorophenyl)thiazol-2-yl)amino)phenol (SKI-II) |
J. Med. Chem. |
59 |
965-984 |
2016 |
Homo sapiens |
26780304 |
1.14.19.17 | 744680 |
From the configurational preference of dihydroceramide desaturase-1 towards DELTA6-unsaturated substrates to the discovery of a new inhibitor |
Chem. Commun. (Camb.) |
53 |
4394-4397 |
2017 |
Homo sapiens |
28379228 |
1.14.19.17 | 745595 |
Gamma-tocotrienol profoundly alters sphingolipids in cancer cells by inhibition of dihydroceramide desaturase and possibly activation of sphingolipid hydrolysis during prolonged treatment |
J. Nutr. Biochem. |
46 |
49-56 |
2017 |
Homo sapiens |
28456081 |
1.14.19.17 | 745511 |
Inhibition of dihydroceramide desaturase activity by the sphingosine kinase inhibitor SKI II |
J. Lipid Res. |
55 |
1711-1720 |
2014 |
Homo sapiens |
24875537 |