EC Number   |
Title |
Organism |
|---|
    1.14.14.32 | Anticancer activity of a novel selective CYP17A1 inhibitor in preclinical models of castrate-resistant prostate cancer |
Homo sapiens |
| 1.14.14.32 | Kinetic processivity of the two-step oxidations of progesterone and pregnenolone to androgens by human cytochrome P450 17A1 |
Homo sapiens |
| 1.14.14.32 | 17-Hydroxylase/C17,20-lyase (CYP17) is not the enzyme responsible for side-chain cleavage of cortisol and its metabolites |
Homo sapiens |
| 1.14.14.32 | 17alpha-Hydroxylase/17,20 lyase inhibitor VN/124-1 inhibits growth of androgen-independent prostate cancer cells via induction of the endoplasmic reticulum stress response |
Homo sapiens |
| 1.14.14.32 | 5alpha-reduced C21 steroids are substrates for human cytochrome P450c17 |
Homo sapiens |
| 1.14.14.32 | Active site proton delivery and the lyase activity of human CYP17A1 |
Homo sapiens |
| 1.14.14.32 | An efficient approach to novel 17-5'-(1',2',4')-oxadiazolyl androstenes via the cyclodehydration of cytotoxic O-steroidacylamidoximes, and an evaluation of their inhibitory action on 17alpha-hydroxylase/C17,20-lyase |
Homo sapiens |
| 1.14.14.32 | An efficient approach to novel 17-5'-(1',2',4')-oxadiazolyl androstenes via the cyclodehydration of cytotoxic O-steroidacylamidoximes, and an evaluation of their inhibitory action on 17alpha-hydroxylase/C17,20-lyase |
Rattus norvegicus |
| 1.14.14.32 | Androgen receptor inactivation contributes to antitumor efficacy of 17{alpha}-hydroxylase/17,20-lyase inhibitor 3beta-hydroxy-17-(1H-benzimidazole-1-yl)androsta-5,16-diene in prostate cancer |
Homo sapiens |
| 1.14.14.32 | At the crossroads of steroid hormone biosynthesis: the role, substrate specificity and evolutionary development of CYP17 |
Papio sp. |
