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EC Number Reaction Commentary Reference
Display the reaction diagram Show all sequences 7.2.4.1a carboxybiotinyl-[protein] + n Na+[side 1] + H+[side 2] = CO2 + a biotinyl-[protein] + n Na+[side 2] - -
Display the reaction diagram Show all sequences 7.2.4.1a carboxybiotinyl-[protein] + n Na+[side 1] + H+[side 2] = CO2 + a biotinyl-[protein] + n Na+[side 2] residue Asp2O3 in its dissociated form binds Na+ and promotes its translocation, while the protonated residue transfers the proton to the acid-labile carboxybiotin which initiates its decarboxylation. Na+ transport by oxaloacetate decarboxylation is accompanied by H+ transport in the opposite direction 686379
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