EC Number   |
Reaction |
Reference |
|---|
    6.3.2.17 | ATP + tetrahydropteroyl-[gamma-Glu]n + L-glutamate = ADP + phosphate + tetrahydropteroyl-[gamma-Glu]n+1 |
formation of a pteroyl-gamma-glutamyl phosphate intermediate |
1076 |
| 6.3.2.17 | ATP + tetrahydropteroyl-[gamma-Glu]n + L-glutamate = ADP + phosphate + tetrahydropteroyl-[gamma-Glu]n+1 |
ordered ter ter mechanism with MgATP binding first to the enzyme, folate second, and glutamate last |
1072, 1075, 1076, 1079 |
| 6.3.2.17 | ATP + tetrahydropteroyl-[gamma-Glu]n + L-glutamate = ADP + phosphate + tetrahydropteroyl-[gamma-Glu]n+1 |
ordered ter-ter mechanism with MgATP binding first, folate second and Glu last |
1061 |
| 6.3.2.17 | ATP + tetrahydropteroyl-[gamma-Glu]n + L-glutamate = ADP + phosphate + tetrahydropteroyl-[gamma-Glu]n+1 |
processive mechanism, in which the folate is the first substrate to bind and the folate-Glu product is the last to be released |
690997 |
| 6.3.2.17 | ATP + tetrahydropteroyl-[gamma-Glu]n + L-glutamate = ADP + phosphate + tetrahydropteroyl-[gamma-Glu]n+1 |
sequential mechanism |
1009, 1077 |
| 6.3.2.17 | ATP + tetrahydropteroyl-[gamma-Glu]n + L-glutamate = ADP + phosphate + tetrahydropteroyl-[gamma-Glu]n+1 |
the products are released in the order: ADP, 5,6,7,8-tetrahydropteroyl-Glu2, phosphate |
1077 |
