5.6.1.5 | ATP + H2O + polypeptide = ADP + phosphate + unfolded polypeptide |
belongs to the AAA-type superfamily and, like EC 3.6.4.5, minus-end-directed kinesin ATPase, is involved in channel gating and polypeptide unfolding before proteolysis in the proteasome. Six ATPase subunits are present in the regulatory particle (RP) of 26S proteasome |
210594, 210595, 210596, 210597, 210598, 210599, 210600, 210601, 210602, 210603, 210604, 210605 |