EC Number   |
Reaction |
Reference |
|---|
   5.6.1.4 | ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end) |
a molecular mechanical model for the Kar3/Vik1 heterodimer is described based on structural, kinetic and motility data revealing a long-range chemomechanical transmission mechanism that resembles a familiar fishing tactic. By this this molecular fishing, ATP-binding to Kar3 dissociates catalytically inactive Vik1 off microtubule to facilitate minus-end sliding of the dimer on the microtubule lattice. When the dimer binds the frayed ends of the microtubules, the fishing channels ATP hydrolysis energy into the microtubule depolymerization by a mechanochemical effect |
713213 |
| 5.6.1.4 | ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end) |
kinetics, comparison of wild-type enzyme and enzyme with N-terminal glutathione S-transferase tag, mechanism |
656259 |
| 5.6.1.4 | ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end) |
mechanism, model of movement |
655330 |
| 5.6.1.4 | ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end) |
model for enzymic coupling of depolymerizing microtubule plus ends to the cell cortex |
655282 |
| 5.6.1.4 | ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end) |
structurally almost identical to EC3.6.4.3 (microtubule-severing ATPase) but the movement it catalyses is towards the minus end of microtubules |
210546, 210548, 210551, 210557, 210558, 210559, 210560, 210561, 210562, 210563, 210565, 210567, 210568, 210569, 210570, 210571, 210572, 210574 |
