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EC Number Reaction Commentary Reference
Display the reaction diagram Show all sequences 5.4.99.2123S rRNA uridine2604 = 23S rRNA pseudouridine2604 - -
Display the reaction diagram Show all sequences 5.4.99.2123S rRNA uridine2604 = 23S rRNA pseudouridine2604 the substrate of RluF undergoes radical structural rearrangements upon binding. The RluF target base lies in an RNA stem rather than in a flexible loop and the substrate conformational change requires disruption of multiple base pairs. This energetically costly process is driven by interactions of the RNA with the protein, a mechanism of RluF is proposed 705143
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