EC Number   |
Reaction |
Reference |
|---|
    5.3.1.23 | S-methyl-5-thio-alpha-D-ribose 1-phosphate = S-methyl-5-thio-D-ribulose 1-phosphate |
- |
- |
| 5.3.1.23 | S-methyl-5-thio-alpha-D-ribose 1-phosphate = S-methyl-5-thio-D-ribulose 1-phosphate |
catalytic reaction mechanism, structure-function relationship, overview. Proposed reaction mechanism of M1Pi proceeds via a cis-phosphoenolate intermediate and through the following steps: (1) transfer of proton from Asp247 to the O4 atom of MTR-1-P, (2) proton abstraction from C2 atom of the substrate by the thiolate anion of Cys167 as well as cleavage of the C1-O4 bond, (3) simultaneous proton abstraction from O2 atom by the deprotonated Asp247 and transfer of proton from the thiol group of Cys167 to C1 atom, and (4) generation of the product, MTRu-1-P |
761764 |
| 5.3.1.23 | S-methyl-5-thio-alpha-D-ribose 1-phosphate = S-methyl-5-thio-D-ribulose 1-phosphate |
proposed reaction mechanism probably including residue Asp240, overview |
-, 760727 |
| 5.3.1.23 | S-methyl-5-thio-alpha-D-ribose 1-phosphate = S-methyl-5-thio-D-ribulose 1-phosphate |
structure-function analysis and catalytic mechanism, overview. Two variants of isomerization mechanism are possible, the enediol and the hydride transfer mechanism, overview |
-, 762331 |
